In humans the P antigen ( also known as globoside ) is the cellular receptor for parvovirus B19 virus that causes Erythema infectiosum ( fifth disease ) in children.
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In 1798, Willan described the occupational disease psoriasis diffusa, which affects the hands and arms of bakers, and in 1799 first described the exanthematous rash of childhood known as erythema infectiosum.
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In humans, the P antigen ( also known as globoside ), one of the many cellular receptors that contribute to a person's blood type, is the cellular receptor for parvovirus B19 virus that causes erythema infectiosum ( fifth disease ) in children.
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Parvovirus B19 was the first pathogenic human parvovirus to be discovered and is best known for causing a childhood exanthem called " " fifth disease " " ( " erythema infectiosum " ), although it is also associated with other diseases including arthritis.
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It was better defined by Anton Tschamer in 1889 as a rubella variant ( " Ortliche Rotheln " ), identified as a distinct condition in 1896 by T . Escherich, and given the name " erythema infectiosum " in 1899 . The virus was first described in 1957 at the University of Pennsylvania by Werner, Brachman et al.
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